VIDEO – MPM Probe Mount NP2a and Alignment Fixture

In case you missed it – here is a recording of the live demo presented by Aaron Solomon, MPM Project Manager, showing the MPM Probe Mount and Alignment Fixture. This hardware simplifies mounting of Neuropixels probes onto the MPM Multi-Probe Micromanipulator and other manipulators*. 


Key points in the video

  • How to install and align two Neuropixels 2.0 probes in the new MPM-ProbeMount-NP2a
  • How to use the alignment fixture with the MPM-ProbeMount-NP2a
  • How to use the alignment fixture with Neuropixels 1.0 probes and the MPM-ProbeMount-1AS “slim”
    At Neuroscience 2021, we heard from users that variations in the 1.0 probes mean that shims are often needed to achieve proper alignment in the mount. This alignment fixture can greatly simplify that process. Learn more about using the alignment fixture with Neuropixels 1.0 probes
  • How to mount the probe holders to your manipulator and use the reference probe for setup.

Attendee questions answered in this video

  • In the second orientation, you show good alignment. Was that just happenstance? As in, is there anything to align the probe to the orientation of the axis of the rod?
  • What is the medial/lateral distance between shanks of the two probes? Is it always fixed or can it be adjusted in case of recordings of more lateral areas in both hemispheres?
  • Can you share a little about how the NP2a Probe Mount was used at beta sites?  How does it add value to researchers?
  • Do you recommend butting the two angles of the probes into the angled pieces of the holder?
  • Would older Neuropixel probes also work with this mount? Or is it solely for the 2.0?
  • I was curious about having two probes close in proximity



This demo and Q&A was led by Aaron Solomon, MPM Project Manager and one of the lead designers of the MPM probe mounts for Neuropixels probes.

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*Note: MPM Probe Mounts are designed for use with the New Scale MPM System. Researchers have successfully adapted them for use with other manipulators. We can’t offer direct support for other manipulators, but will answer questions if we can, and facilitate the open flow of ideas among our users.