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How to use the alignment fixture

The alignment fixture simplifies mounting of Neuropixels probes onto the MPM Multi-Probe Micromanipulator and other manipulators*. This recording of the live demo shows the use of the Alignment Fixture with two different probe mounts: 

    • MPM-Probe Mount-NP2a for Neuropixels 2.0 (alpha phase) probes.
      NOTE: The NP2a probe mount is no longer available. A probe mount for the Neuropixels 2.0 probes (production release) is in development.
    • MPM-Probe Mount-1AS for Neuropixels 1.0 probes


Key points in the video

  • How to install and align two Neuropixels 2.0 (alpha phase) probes in the MPM-ProbeMount-NP2a
  • How to use the alignment fixture with the MPM-ProbeMount-NP2(a)
  • How to use the alignment fixture with Neuropixels 1.0 probes and the MPM-ProbeMount-1AS “slim”
    Learn more about using the alignment fixture with Neuropixels 1.0 probes
  • How to mount the probe holders to your manipulator and use the reference probe for setup.



This demo and Q&A was led by Aaron Solomon, MPM Project Manager and one of the lead designers of the MPM probe mounts for Neuropixels probes.

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*Note: MPM Probe Mounts are designed for use with the New Scale MPM System. Researchers have successfully adapted them for use with other manipulators. We can’t offer direct support for other manipulators, but will answer questions if we can, and facilitate the open flow of ideas among our users.