Compact Multi-Probe Micromanipulator (MPM) System allows neuroscience researchers to quickly and precisely position multiple Neuropixels 2.0 probes for neural recording
New Scale Technologies has announced a probe mounting kit for Neuropixels 2.0 probes (alpha phase) on the company’s MPM Multi-Probe Micromanipulator System for neural recording.
The newest probe mount MPM-Probe_Mount-NP2a allows one or two Neuropixels 2.0 probes to be mounted on each manipulator arm in the MPM System.
The MPM System enables precise positioning of neural probes, optical fibers and more. The compact design supports multiple manipulator arms in a compact space. The ability to mount two Neuropixels 2.0 probes on each manipulator arm further increases the density of probes that can be achieved.
NOTE: New Scale also provides a probe mount for Neuropixels 1.0 probes.
The MPM System is the only micromanipulator designed specifically for high-density silicon probes. Neuroscience researchers at the Allen Institute for Brain Science, Stanford University, Caltech, MIT, Purdue, the Max Delbrück Center, Scripps Research and more are using the MPM System to position up to eight silicon neural probes simultaneously. The new Virtual Coordinate System software allows all probes to move in a common stereotactic coordinate space.
The probe holder MPM-Probe_Mount-NP2a is designed for the Neuropixels 2.0 probes as they are shipping in alpha phase, without a dove-tail cap.
The probe holder is designed to work with the New Scale MPM System, but can be adapted for use with other manipulators. Learn more about New Scale neural probe mounts.
MPM System with three manipulator arms
MPM Probe Mount NP2a shown with two Neuropixels 2.0 Alpha Phase Probes (preliminary). The probe mount can accommodate one or two probes.
Using the MPM Probe Mount NP2a
Learn how to install Neuropixels 2.0 probes into the probe holder, attach the head stage PCB to the probes, and check the alignment of both probes before affixing the probe holder to the micro manipulator system.
Using the MPM Probe Mount 1AS
Learn how to install and align Neuropixels 1.0 probes in the probe holder. By clamping the probe as far away from the shank as possible, rather than by the silicon spacer or dovetail cap, this probe holder allows researchers to maximize the density of probes in their multi-probe neural recording experiments.
Hardware Guides and Drawings
Download hardware guides and drawings for the MPM Probe Mount NP2a and alignment fixture (registration required).
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The MPM Multi-Probe Micromanipulator
The MPM System provides convenient, automated positioning of multiple neural probes for acute in-vivo recording. Maximize productivity and precision in electrophysiology and optogenetics research. The compact design enables independent positioning of multiple probes in the smallest space.