Modular Insertion System (MIS)
Next Generation Silicon Probe Insertion System for Neuroscience
Accelerate your research with more micromanipulators and more probes for more data.
In collaboration with Allen Institute for Neural Dynamics, we’re excited to introduce the Modular Insertion System (MIS)—a next-generation multi-probe insertion system for acute in vivo electrophysiology recordings. Building on our Multi-Probe Micromanipulator (MPM) System, the new MIS system allows researchers to collect more data in less time, supporting:
- Up to 25 neuropixel probes for the most recording sites in the smallest space
- Laser modules used for optogenetics research
- Microscope modules to guide safe probe insertion
“Our goal with the MIS is to provide more flexible approach angles, enable the insertion of more probes as recording devices become smaller, provide more open space for behavioral hardware, and allow for easier maintenance during and between experiments.”
Josh Siegle, Senior Scientist at the Allen Institute for Neural Dynamics.
See the MIS in Action.
Book a demo with our team to see how our technology can help you collect more data in less time.
Modularity = Flexibility and Reproducibility
The MIS offers 3 standard modules, including a probe, laser and microscope module.
- Probe modules use stable, high-precision motorized stages to position Neuropixels probes to support acute in-vivo recordings with silicon probes.
- Laser modules similarly use M3 stages to position lasers, allowing for tissue stimulation to support optogenetics research.
- Microscope modules allow users to visualize probe insertions and guide laser placements safely and accurately.
These standard modules help standardize research methods between different institutions, allowing greater collaboration and reproducibility of experiments across different labs.
Pathfinder Software
Stereotactic PC Control of Each Manipulator
Effortlessly command each motorized stage through our user-friendly Pathfinder Software featuring a Virtual Coordinate System (VCS). This empowers you to independently and autonomously control every probe within a unified stereotactic coordinate framework.
Trajectory Planning tools offer a visual representation of probe locations and facilitate the design of insertion pathways. Automatically compute the approach angle for each probe, informed by simulated experiments conducted on your workstation. Predict and prevent potential probe collisions, and execute experiments with exceptional reproducibility.
Data acquisition applications provide real-time heatmaps to verify probe positioning, ensuring accurate channel depth.
